Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985444 | 0.95 | CNOT7 (0.41) | CNOT7MAPK1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7974274 | 0.85 | CNOT7 (0.45) | CNOT7MAPK1LMNASMN1; SMN2KMT2A | |
| SCHEMBL7984486 | 0.83 | CNOT7 (0.54) | CNOT7MAPK1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7984463 | 0.83 | KDM4E (0.53) | CNOT7MAPK1LMNASMN1; SMN2KMT2A | |
| SCHEMBL7974644 | 0.82 | SMN1; SMN2 (0.55) | CNOT7SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL7973916 | 0.80 | LMNA (0.43) | LMNASMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL7988183 | 0.78 | SMN1; SMN2 (0.48) | LMNAL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7985867 | 0.78 | GAA (0.53) | LMNASMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL7985450 | 0.78 | CNOT7 (0.48) | CNOT7LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7985770 | 0.78 | CNOT7 (0.50) | CNOT7MAPK1LMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |