Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974262 | 0.86 | ALDH1A1 (0.45) | CNOT7PARNSMN1; SMN2HTTTP53 | |
| SCHEMBL7984210 | 0.85 | GRIN1 (0.43) | CNOT7PARNGRIN1GRIN2BRXFP1 | |
| SCHEMBL7984758 | 0.85 | SMN1; SMN2 (0.51) | CNOT7PARNSMN1; SMN2GLAHTT | |
| SCHEMBL7975254 | 0.84 | CNOT7 (0.55) | CNOT7PARNSMN1; SMN2RXFP1HPGD | |
| SCHEMBL7984496 | 0.83 | HPGD (0.45) | GRIN1GRIN2BMETSMN1; SMN2GLA | |
| SCHEMBL7984516 | 0.83 | TP53 (0.53) | TP53RXFP1 | |
| SCHEMBL7985654 | 0.81 | CNOT7 (0.42) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7984380 | 0.79 | CYP11B1 (0.40) | CNOT7PARNSMN1; SMN2HTTHPGD | |
| SCHEMBL7987439 | 0.78 | CNOT7 (0.43) | CNOT7PARNSMN1; SMN2HTTTP53 | |
| SCHEMBL7973938 | 0.78 | CNOT7 (0.48) | CNOT7PARNSMN1; SMN2L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |