Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974262 | 0.89 | ALDH1A1 (0.45) | CYP11B1CYP11B2CNOT7PARNALDH1A1 | |
| SCHEMBL7987439 | 0.89 | CNOT7 (0.43) | CYP11B1CYP11B2CNOT7PARNALDH1A1 | |
| SCHEMBL7987963 | 0.88 | CNOT7 (0.38) | CNOT7PARNALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7975254 | 0.85 | CNOT7 (0.55) | CNOT7PARNALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7985247 | 0.83 | HSP90AA1 (0.45) | LMNASMN1; SMN2KDM4E | |
| SCHEMBL7985523 | 0.83 | TDP1 (0.39) | CNOT7PARNALDH1A1LMNAHTT | |
| SCHEMBL7988132 | 0.82 | CNOT7 (0.44) | CNOT7PARNALDH1A1LMNAHPGD | |
| SCHEMBL7984530 | 0.82 | HPGD (0.46) | CYP11B2CNOT7PARNALDH1A1HTT | |
| SCHEMBL7974273 | 0.82 | TNF (0.44) | CNOT7PARNALDH1A1LMNAHTT | |
| SCHEMBL7985654 | 0.82 | CNOT7 (0.42) | CNOT7PARNALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |