Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717717 | 1.00 | LIPG (0.53) | LIPGTHRATHRBMEN1APAF1 | |
| SCHEMBL9717720 | 1.00 | LIPG (0.53) | LIPGTHRATHRBMEN1APAF1 | |
| SCHEMBL27164184 | 0.98 | LIPG (0.50) | LIPGTHRATHRBMEN1APAF1 | |
| SCHEMBL10643236 | 0.93 | CYP3A4 (0.47) | LIPGTHRATHRBMEN1APAF1 | |
| SCHEMBL14466202 | 0.91 | HPGD (0.45) | LIPGMEN1MAPTMAPK1HTT | |
| SCHEMBL5072960 | 0.86 | ALOX5 (0.51) | LIPGMEN1MAPTHTTKMT2A | |
| SCHEMBL2283264 | 0.86 | ALOX5 (0.51) | LIPGMEN1MAPTHTTKMT2A | |
| SCHEMBL5078103 | 0.86 | ALOX5 (0.51) | LIPGMEN1MAPTHTTKMT2A | |
| SCHEMBL5075323 | 0.86 | ALOX5 (0.51) | LIPGMEN1MAPTHTTKMT2A | |
| SCHEMBL9330950 | 0.82 | LIPG (0.59) | LIPGTHRATHRBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809714-A4 | MODIFIERS FOR ALDOXIME EXTRACTANT OF METAL VALUES | HENKEL CORP (US) | 1998-05-06 | — | — | EP | claimed |
| CN-1175982-A | Modifier for aldoxime extractant of metal useful component | HENKEL CORP (US) | 1998-03-11 | — | — | CN | claimed |
| EP-0809714-A1 | MODIFIERS FOR ALDOXIME EXTRACTANT OF METAL VALUES | HENKEL CORPORATION (US) | 1997-12-03 | — | — | EP | claimed |
| WO-1996025525-A1 | MODIFIERS FOR ALDOXIME EXTRACTANT OF METAL VALUES | HENKEL CORPORATION (US) | 1996-08-22 | — | — | WO | claimed |
| US-6277300-B1 | AN EXTRACTANT FOR EXTRACTING METALS FROM AQUEOUS SOLUTIONS OF METAL SALTS COMPRISING AT LEAST ONE O-HYDROXYARYLOXIME CONTAINING AT LEAST 5 ALIPHATIC CARBON ATOMS AND ATLEAST ONE HIGHLY BRANCHED ESTER CONTAINING 10 TO 30 CARBON ATOMS | ZENECA LIMITED (GB) | 2001-08-21 | — | — | US | disclosed |
| US-6113804-A | MIXTURES OF O-HYDROXYARYLOXIMES IN ACIDIC ALIPHATIC HYDROCARBON SOLUTION AND ALIPHATIC OR ALIPHATIC-AROMATIC ESTERS, FOR CHELATION OF COPPER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2000-09-05 | — | — | US | disclosed |
| US-5281336-A | Contacting solution with organic solvent containing o-hydroxyaryloxime extractant and alcohol or ester, separating aqueous phase, contacting organic phase with mineral acid, separating metal in form of salt | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-25 | — | — | US | disclosed |
| US-5176843-A | O-hydroxyaryloximes, alcohol or ester, o-hydroxyarylketoximes; extracting copper | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-05 | — | — | US | disclosed |
| US-4978788-A | COPPER AS PERCHLORATE USING O-HYDROXYARYLOXIMES AND BRANCHED ALIPHATIC OR AROMATIC ALCOHOLS OR ESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-18 | — | — | US | disclosed |
| EP-0202833-A2 | Composition and use of the composition for the extraction of metals from aqueous solutions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-26 | — | — | EP | disclosed |