Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27164184 | 0.95 | LIPG (0.50) | CYP3A4CYP2D6CYP2C9LIPGHPGD | |
| SCHEMBL9717717 | 0.93 | LIPG (0.53) | CYP3A4CYP2D6CYP2C9LIPGMAPK1 | |
| SCHEMBL7984518 | 0.93 | LIPG (0.53) | CYP3A4CYP2D6CYP2C9LIPGMAPK1 | |
| SCHEMBL9717720 | 0.93 | LIPG (0.53) | CYP3A4CYP2D6CYP2C9LIPGMAPK1 | |
| SCHEMBL14466202 | 0.87 | HPGD (0.45) | CYP3A4CYP2D6CYP2C9LIPGHPGD | |
| SCHEMBL27796003 | 0.85 | ALOX12 (0.49) | CYP3A4CYP2D6CYP2C9MEN1KMT2A | |
| SCHEMBL2161080 | 0.81 | USP2 (0.47) | CYP3A4CYP2D6CYP2C9HPGDLMNA | |
| SCHEMBL10655491 | 0.81 | USP2 (0.47) | CYP3A4CYP2D6CYP2C9HPGDLMNA | |
| SCHEMBL2161081 | 0.81 | USP2 (0.47) | CYP3A4CYP2D6CYP2C9HPGDLMNA | |
| SCHEMBL5072960 | 0.79 | ALOX5 (0.51) | CYP3A4LIPGTSHRHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739118-A | Process for the preparation of hydroxybenzaldoxime O-ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-19 | — | — | US | disclosed |
| EP-0218123-A1 | Process for the preparation of hydroxy-benzaldoxime-O-ethers | BAYER AG (DE) | 1987-04-15 | — | — | EP | disclosed |