Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18891533 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16332952 | 0.75 | GRM5 (0.39) | ALDH1A1MEN1KMT2AGRM5 | |
| SCHEMBL21159432 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AGRM5CYP1A2 | |
| SCHEMBL13723366 | 0.75 | XIAP (0.50) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11712255 | 0.75 | RAB9A (0.55) | ALDH1A1MEN1KMT2AGRM5 | |
| SCHEMBL1861757 | 0.75 | RAB9A (0.55) | ALDH1A1MEN1KMT2AGRM5 | |
| Pyridine SCHEMBL28827278 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14547682 | 0.71 | — | — | |
| SCHEMBL2570548 | 0.71 | — | — | |
| SCHEMBL29512488 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |