Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GRM5 | P41594 | 5/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861757 | 1.00 | RAB9A (0.55) | RAB9AMEN1KMT2AGRM5CCR1 | |
| SCHEMBL18891533 | 0.84 | ALDH1A1 (0.44) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27665125 | 0.80 | RAB9A (0.52) | RAB9AMEN1KMT2AGRM5CCR1 | |
| SCHEMBL14182349 | 0.79 | KMT2A (0.50) | RAB9AMEN1KMT2AGRM5CCR1 | |
| SCHEMBL7984520 | 0.75 | FFAR2 (0.40) | MEN1KMT2AGRM5ALDH1A1 | |
| SCHEMBL21159432 | 0.75 | ALDH1A1 (0.49) | MEN1KMT2AGRM5ALDH1A1HPGD | |
| SCHEMBL13723366 | 0.75 | XIAP (0.50) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16332952 | 0.75 | GRM5 (0.39) | MEN1KMT2AGRM5ALDH1A1KDM4E | |
| SCHEMBL229747 | 0.75 | RAB9A (0.59) | RAB9AMEN1KMT2AGRM5CCR1 | |
| SCHEMBL15626076 | 0.75 | SYK (0.37) | RAB9AMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021437-A | 6-Ethylamino-2-picoline from 6-acetamido-2-picoline | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |