Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998776 | 0.76 | HPRT1 (0.48) | HSD17B10ALDH1A1HIF1ACYP1B1HPGD | |
| SCHEMBL29975451 | 0.75 | KDM4E (0.39) | HSD17B10ALDH1A1CYP1B1HPGDTSHR | |
| SCHEMBL4845522 | 0.74 | ALDH1A1 (0.89) | HSD17B10ALDH1A1HIF1ACYP1B1HPGD | |
| SCHEMBL4856624 | 0.74 | ALDH1A1 (1.00) | HSD17B10ALDH1A1HIF1ACYP1B1HPGD | |
| Dibenz[A,H]Anthracene SCHEMBL156100 | 0.74 | ALDH1A1 (1.00) | HSD17B10ALDH1A1HIF1ACYP1B1HPGD | |
| Dibenz[A,H]Anthracene SCHEMBL29777008 | 0.74 | ALDH1A1 (1.00) | HSD17B10ALDH1A1HIF1ACYP1B1HPGD | |
| Dibenz[A,H]Anthracene SCHEMBL29392838 | 0.74 | ALDH1A1 (1.00) | HSD17B10ALDH1A1HIF1ACYP1B1HPGD | |
| SCHEMBL31010417 | 0.72 | ALDH1A1 (0.84) | HSD17B10ALDH1A1HIF1ACYP1B1HPGD | |
| SCHEMBL4845352 | 0.72 | ALDH1A1 (0.84) | HSD17B10ALDH1A1HIF1ACYP1B1HPGD | |
| SCHEMBL31010418 | 0.72 | ALDH1A1 (0.84) | HSD17B10ALDH1A1HIF1ACYP1B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294380-B1 | Liver cell clones for use in extracorporeal liver-assist device | JMS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1063289-A1 | Liver cell clones for artifical liver and extracorporeal liver assist device | JMS Co., Ltd. (JP) | 2000-12-27 | — | — | EP | disclosed |