Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997664 | 0.87 | GFER (0.36) | ALDH1A1MEN1KMT2AGFERCYP1A2 | |
| SCHEMBL7994261 | 0.78 | ALDH1A1 (0.37) | ALDH1A1POLBMEN1KMT2AGFER | |
| SCHEMBL6865524 | 0.76 | NPC1 (0.34) | LMNAHTTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6867948 | 0.75 | NPC1 (0.33) | LMNAHTTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL8307701 | 0.72 | ALDH1A1 (0.44) | ALDH1A1POLBKMT2AGFERLMNA | |
| Hydrochloric Acid SCHEMBL6869270 | 0.71 | NPC1 (0.35) | LMNAHTTRAB9ANPC1 | |
| SCHEMBL7005344 | 0.69 | MAPK1 (0.39) | ALDH1A1POLBMEN1KMT2ACYP1A2 | |
| SCHEMBL7983461 | 0.69 | HPGD (0.38) | ALDH1A1POLBMEN1KMT2AGFER | |
| Hydrochloric Acid SCHEMBL7010030 | 0.69 | MAPK1 (0.38) | ALDH1A1POLBMEN1KMT2ACYP1A2 | |
| SCHEMBL7007419 | 0.69 | GRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |