Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997302 | 0.94 | KDM4E (0.40) | KDM4EFKBP1APOLBMEN1KMT2A | |
| SCHEMBL27406398 | 0.75 | MEN1 (0.50) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7947324 | 0.73 | MEN1 (0.48) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL27404097 | 0.73 | ACHE (0.44) | KDM4EPOLBMEN1KMT2ALMNA | |
| SCHEMBL7001262 | 0.72 | MEN1 (0.57) | KDM4EPOLBMEN1KMT2A | |
| SCHEMBL7985088 | 0.71 | MAPK1 (0.38) | MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL6992897 | 0.70 | ALDH1A1 (0.47) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6996711 | 0.70 | ACHE (0.46) | KDM4EPOLBMEN1KMT2ALMNA | |
| SCHEMBL7961148 | 0.70 | MEN1 (0.46) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6993974 | 0.69 | HRH1 (0.40) | KDM4EALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211199-B1 | HISTAMINE AND TACHYKININ RECEPTOR ANTAGONISTS; ANTIASTHMATICS, ANTIEMETICS; RESPIRATORY SYSTEM DISORDERS, INFLAMMATORY BOWEL DISEASE, CONJUNCTIVITIS | AVENTIS PHARMACEUTICALS INC. | 2001-04-03 | — | — | US | disclosed |