SCHEMBL7984638

SCHEMBL7984638

NC(c1ccccc1)C(O)c1ccc(OC(F)F)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2C P18825 1/20 0.43
HIF1A Q16665 1/20 0.43
KDM4E B2RXH2 1/20 0.43
DPP4 P27487 2/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
TEAD4 Q15561 1/20 0.39
ALOX15 P16050 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
DAGLA Q9Y4D2 1/20 0.39
HTT P42858 1/20 0.38
GAA P10253 1/20 0.38
AOC3 Q16853 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GFER P55789 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7267014 0.80 SRD5A2 (0.47) LMNAALDH1A1MAPTKMT2AMEN1
SCHEMBL3831819 0.80 ALDH1A1 (0.44) LMNADPP4ALDH1A1MAPTKMT2A
SCHEMBL2763479 0.80 DPP4 (0.65) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL3802461 0.80 DPP4 (0.65) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL1131702 0.80 DPP4 (0.65) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL17514076 0.80 DPP4 (0.65) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL186279 0.80 DPP4 (0.65) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL82461 0.80 DPP4 (0.65) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL14959742 0.80 DPP4 (0.65) LMNAADRA2AADRA2CHIF1AKDM4E
SCHEMBL82462 0.80 DPP4 (0.65) LMNAADRA2AADRA2CHIF1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172093-B1 PESTICIDES, INSECTICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-5969147-A Substituted biphenyloxazolines BAYER AKTIENGESELLSCHAFT (DE) 1999-10-19 US disclosed
EP-0696584-B1 Substituted biphenyloxazolines and their use as fungicides BAYER AG (DE) 1999-01-20 EP disclosed
EP-0696584-A1 Substituted biphenyloxazolines and their use as fungicides BAYER AG (DE) 1996-02-14 EP disclosed