SCHEMBL1131702

SCHEMBL1131702

N[C@@H](c1ccccc1)[C@H](O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.65
KDM4E B2RXH2 2/20 0.62
ADRA2A P08913 1/20 0.62
ADRA2C P18825 1/20 0.62
LMNA P02545 1/20 0.62
HIF1A Q16665 1/20 0.62
ALDH1A1 P00352 2/20 0.60
AOC3 Q16853 6/20 0.52
F2 P00734 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
CHRM2 P08172 1/20 0.46
ADRA1A P35348 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82461 1.00 DPP4 (0.65) DPP4KDM4EADRA2AADRA2CLMNA
SCHEMBL2438955 1.00 DPP4 (0.65) DPP4KDM4EADRA2AADRA2CLMNA
SCHEMBL2763479 1.00 DPP4 (0.65) DPP4KDM4EADRA2AADRA2CLMNA
SCHEMBL3802461 1.00 DPP4 (0.65) DPP4KDM4EADRA2AADRA2CLMNA
SCHEMBL186279 1.00 DPP4 (0.65) DPP4KDM4EADRA2AADRA2CLMNA
SCHEMBL82462 1.00 DPP4 (0.65) DPP4KDM4EADRA2AADRA2CLMNA
SCHEMBL17514076 1.00 DPP4 (0.65) DPP4KDM4EADRA2AADRA2CLMNA
SCHEMBL14959742 1.00 DPP4 (0.65) DPP4KDM4EADRA2AADRA2CLMNA
SCHEMBL8120379 0.89 DPP4 (0.52) DPP4KDM4EADRA2AADRA2CLMNA
Alcohol SCHEMBL8325116 0.89 KDM4E (0.57) DPP4KDM4EADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4624455-A1 PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) 2025-10-01 EP claimed
US-20250276986-A1 PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF Kangbaida (Sichuan) Biotechnology Co., Ltd (CN) 2025-09-04 US claimed
CN-119119087-A Chiral binuclear copper complex with benzo [ c ] cinnoline skeleton and preparation method thereof 中国科学院上海有机化学研究所 2024-12-13 CN claimed
WO-2024109801-A1 PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF 成都百裕制药股份有限公司 2024-05-30 WO claimed
CN-117120418-A Process for the preparation of compound (I) 百时美施贵宝公司 2023-11-24 CN claimed
CN-114573489-B Separation method of carboprost 河北化工医药职业技术学院 2023-08-22 CN claimed
CN-115465853-B Orange light carbon dot based on citric acid and chiral 2-amino-1, 2-diphenyl ethanol and preparation method and application thereof 西华大学 2023-06-20 CN claimed
CN-115465853-A Orange light carbon dot based on citric acid and chiral 2-amino-1, 2-diphenylethanol and preparation method and application thereof 西华大学 2022-12-13 CN claimed
CN-114920669-A Synthesis method of N-methyl-N-benzyloxycarbonyl-L-aspartic acid (4-tert-butyl ester) dicyclohexylamine salt 吉尔多肽生物制药(大连市)有限公司 2022-08-19 CN claimed
CN-114591261-A Synthesis method of chiral benzyl carboxylate compound 上海药坦药物研究开发有限公司 2022-06-07 CN claimed
EP-1928878-A1 METHODS FOR THE PREPARATION OF HCV POLYMERASE INHIBITORS PFIZER INC. (US) 2008-06-11 EP claimed
US-20080090907-A1 Crystal Comprising (2R)-2-Propyloctanoic Acid and Amine ONO PHARMACEUTICAL CO., LTD. (JP) 2008-04-17 US claimed
WO-2007023381-A1 METHODS FOR THE PREPARATION OF HCV POLYMERASE INHIBITORS PFIZER INC. (US) 2007-03-01 WO claimed
EP-1741697-A1 CRYSTAL COMPRISING (2R)-2-PROPYLOCTOIC ACID AND AMINE ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-10 EP claimed
US-20060020022-A1 Enantioselective separation method PHARMACIA & UPJOHN COMPANY LLC 2006-01-26 US claimed
EP-1324975-B1 DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS BRISTOL MYERS SQUIBB CO (US) 2005-11-16 EP claimed
US-20050020834-A1 Method for preparation of sulphostin and its analogue or intermediates thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-01-27 US claimed
EP-1457494-A1 PROCESSES FOR PREPARATION OF SULPHOSTIN AND ITS ANALOGUES OR INTERMEDIATES THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2004-09-15 EP claimed
WO-2004020402-A1 SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE DE NOVO PHARMACEUTICALS LIMITED (GB) 2004-03-11 WO claimed
US-20020111512-A1 Dynamic resolution of isomers and resolved isomers BRISTOL-MYERS SQUIBB COMPANY 2002-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020834-A1 Method for preparation of sulphostin and its analogue or intermediates thereof SOST, PTMS, FGF23 DPP4 987/4885KDM4E 3668/4885ADRA2A 4343/4885
US-20080090907-A1 Crystal Comprising (2R)-2-Propyloctanoic Acid and Amine TAS2R5, FFAR2, HRH2 DPP4 1510/4885KDM4E 2188/4885ADRA2A 43/4885
US-20020111512-A1 Dynamic resolution of isomers and resolved isomers DHCR24, LPAR1, SLC7A1 DPP4 4439/4885KDM4E 4215/4885ADRA2A 337/4885
US-20250276986-A1 PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF PIN1, DHPS, PPOX DPP4 640/4885KDM4E 1368/4885ADRA2A 4185/4885
US-20060020022-A1 Enantioselective separation method SLC7A1, SLC10A1, DHCR7 DPP4 814/4885KDM4E 4250/4885ADRA2A 586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.