Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.44 |
| ▸ | F10 | P00742 | 10/20 | 0.44 |
| ▸ | PLG | P00747 | 7/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028389 | 0.88 | BRD9 (0.45) | F10BRD9CCNCCDK8HTR1A | |
| Hydrochloric Acid SCHEMBL7985036 | 0.82 | F2 (0.63) | F2F10PLGBRD9PRSS1 | |
| SCHEMBL7426210 | 0.81 | F2 (0.46) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7427026 | 0.76 | F2 (0.43) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7426354 | 0.76 | F2 (0.55) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7981313 | 0.76 | ALDH1A1 (0.44) | F2F10PLG | |
| SCHEMBL7984703 | 0.75 | F2 (0.64) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7426925 | 0.74 | F2 (0.72) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7978114 | 0.73 | BRD9 (0.44) | F10BRD9CCNCCDK8BRPF1 | |
| SCHEMBL4586702 | 0.73 | ALDH1A1 (0.51) | F10BRD9HTR1AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |