Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.46 |
| ▸ | F10 | P00742 | 10/20 | 0.45 |
| ▸ | PLG | P00747 | 7/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427026 | 0.83 | F2 (0.43) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8028137 | 0.83 | CNR2 (0.48) | F2CNR2KDM4ERAD52IDH1 | |
| SCHEMBL7426354 | 0.83 | F2 (0.55) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7981313 | 0.82 | ALDH1A1 (0.44) | F2F10PLGCNR2KDM4E | |
| SCHEMBL7978111 | 0.81 | F2 (0.44) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7426925 | 0.78 | F2 (0.72) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7981516 | 0.78 | BRPF1 (0.42) | F2F10PLGBRPF1CNR2 | |
| SCHEMBL6157976 | 0.77 | NPC1 (0.59) | F2CNR2KDM4ERAD52 | |
| SCHEMBL7981348 | 0.77 | BRPF1 (0.56) | F2BRPF1 | |
| SCHEMBL7984703 | 0.76 | F2 (0.64) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| EP-1071669-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054313-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |