Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987447 | 0.91 | GPR119 (0.31) | LTB4R | |
| SCHEMBL8128898 | 0.81 | CAPN1 (0.39) | — | |
| SCHEMBL7984772 | 0.78 | FNTA (0.44) | FNTAPGGT1B | |
| SCHEMBL8143718 | 0.77 | P2RX3 (0.35) | — | |
| SCHEMBL8134169 | 0.76 | P2RX3 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL8133580 | 0.75 | FNTA (0.37) | FNTAPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8134677 | 0.75 | ITGB1 (0.33) | — | |
| SCHEMBL8112875 | 0.75 | FNTA (0.40) | FNTAPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8125473 | 0.75 | CCR3 (0.38) | FNTAPGGT1BSMN1; SMN2 | |
| SCHEMBL8131691 | 0.75 | FNTA (0.37) | FNTAPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009125-A1 | NOVEL 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |