Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998255 | 0.85 | HSP90AA1 (0.33) | CYP3A4HPGDL3MBTL1HIF1AHSD17B10 | |
| SCHEMBL7998258 | 0.82 | HSP90AA1 (0.33) | CYP3A4HPGDL3MBTL1HIF1AHSD17B10 | |
| Sulfuric Acid SCHEMBL7984779 | 0.82 | HPGD (0.56) | CYP3A4HPGDL3MBTL1HIF1AHSD17B10 | |
| SCHEMBL19065044 | 0.73 | L3MBTL1 (0.65) | CYP3A4HPGDL3MBTL1HIF1AHSD17B10 | |
| SCHEMBL7994830 | 0.72 | CYP1A2 (0.39) | HPGDHIF1AHSD17B10TSHRCYP1A2 | |
| SCHEMBL29403351 | 0.70 | HSD17B10 (1.00) | CYP3A4HPGDL3MBTL1HIF1AHSD17B10 | |
| SCHEMBL99213 | 0.70 | HSD17B10 (1.00) | CYP3A4HPGDL3MBTL1HIF1AHSD17B10 | |
| SCHEMBL29531544 | 0.70 | HSD17B10 (1.00) | CYP3A4HPGDL3MBTL1HIF1AHSD17B10 | |
| SCHEMBL29382459 | 0.70 | HSD17B10 (1.00) | CYP3A4HPGDL3MBTL1HIF1AHSD17B10 | |
| Acetone SCHEMBL4624685 | 0.70 | HPGD (0.81) | CYP3A4HPGDL3MBTL1HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294380-B1 | Liver cell clones for use in extracorporeal liver-assist device | JMS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1063289-A1 | Liver cell clones for artifical liver and extracorporeal liver assist device | JMS Co., Ltd. (JP) | 2000-12-27 | — | — | EP | disclosed |