Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7994836 | 0.82 | ERBB2 (0.43) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL30363574 | 0.77 | MEN1 (0.51) | CYP1A2HPGDKDM4EAKR1B1TDP1 | |
| SCHEMBL4630262 | 0.76 | ALDH1A1 (0.50) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL7794322 | 0.75 | CYP1A2 (0.48) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL7998258 | 0.73 | HSP90AA1 (0.33) | CYP1A2ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL7998255 | 0.73 | HSP90AA1 (0.33) | CYP1A2ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL17183137 | 0.73 | HSD17B10 (0.50) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL7984777 | 0.72 | CYP3A4 (0.51) | CYP1A2ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL2314306 | 0.72 | CYP1A2 (0.46) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL27779333 | 0.70 | ALDH1A1 (0.41) | CYP1A2ERBB2FYNMAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294380-B1 | Liver cell clones for use in extracorporeal liver-assist device | JMS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1063289-A1 | Liver cell clones for artifical liver and extracorporeal liver assist device | JMS Co., Ltd. (JP) | 2000-12-27 | — | — | EP | disclosed |