Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | PON1 | P27169 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12354660 | 0.84 | ALDH1A1 (0.42) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL11347457 | 0.74 | KDM4E (0.50) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL1445682 | 0.73 | GABRA1 (0.40) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL31369133 | 0.72 | KIF11 (0.65) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30577796 | 0.72 | KIF11 (0.65) | ALDH1A1NPC1HPGDTDP1KIF11 | |
| SCHEMBL25243502 | 0.72 | KIF11 (0.65) | ALDH1A1NPC1HPGDTDP1KIF11 | |
| SCHEMBL12181810 | 0.72 | PON1 (0.57) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL12181806 | 0.72 | PON1 (0.45) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL31369143 | 0.72 | KIF11 (0.65) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30577798 | 0.72 | KIF11 (0.65) | ALDH1A1NPC1HPGDTDP1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |