Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MC1R | Q01726 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995803 | 0.86 | SCN9A (0.44) | SCN9APDK2CA12CA1CA2 | |
| SCHEMBL8001577 | 0.79 | BRD4 (0.47) | SCN9ABRD4ADRB2ALDH1A1HPGD | |
| SCHEMBL7984211 | 0.79 | STING1 (0.43) | HCKMAPK14 | |
| SCHEMBL7984853 | 0.78 | SCN9A (0.46) | SCN9APDK2CA12CA1CA2 | |
| SCHEMBL7995719 | 0.77 | SCN9A (0.45) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL7994019 | 0.77 | SCN9A (0.48) | SCN9APDK2CA12CA1CA2 | |
| SCHEMBL7995494 | 0.76 | SCN9A (0.48) | SCN9APDK2CA12CA1CA2 | |
| SCHEMBL7983762 | 0.74 | SCN9A (0.44) | SCN9APDK2CA12CA1CA2 | |
| SCHEMBL8001602 | 0.74 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL7995700 | 0.73 | SCN9A (0.43) | SCN9APDK2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |