Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994019 | 0.89 | SCN9A (0.48) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL13744590 | 0.85 | MEN1 (0.51) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL20630423 | 0.85 | SCN9A (0.51) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL7997358 | 0.84 | MEN1 (0.46) | MEN1PKMKMT2A | |
| SCHEMBL13744814 | 0.84 | DRD2 (0.49) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL1682258 | 0.82 | SCN9A (0.60) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL18687756 | 0.80 | ADRB2 (0.51) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL15869790 | 0.79 | ALDH1A1 (0.55) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL8001577 | 0.79 | BRD4 (0.47) | SCN9AADRB2PKMKMT2A | |
| SCHEMBL1683198 | 0.79 | KMT2A (0.52) | SCN9ACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |