Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.43 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30147174 | 0.90 | TSHR (0.49) | MAPTNPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL29176585 | 0.86 | EPHA2 (0.47) | MAPTNPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL29176583 | 0.86 | EPHA2 (0.47) | MAPTNPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL7995090 | 0.85 | FKBP1A (0.57) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7995095 | 0.85 | FKBP1A (0.57) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL30147124 | 0.84 | ALDH1A1 (0.48) | MAPTNPSR1FKBP1AALDH1A1TSHR | |
| SCHEMBL30147182 | 0.81 | EPHA2 (0.46) | MAPTNPSR1FKBP1AALDH1A1TSHR | |
| SCHEMBL15848655 | 0.81 | HCRTR2 (0.60) | HCRTR2 | |
| SCHEMBL15848653 | 0.81 | HCRTR2 (0.60) | HCRTR2 | |
| SCHEMBL7984949 | 0.79 | FKBP1A (0.61) | FKBP1AFKBP4FKBP5HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284779-B1 | NERVOUS SYSTEM DISORDERS | SCHERING AKTIIENGESELLSCHAFT (DE) | 2001-09-04 | — | — | US | disclosed |
| WO-2000046222-A1 | HETEROAROMATIC COMPOUNDS WITH NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-08-10 | — | — | WO | disclosed |