Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 13/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.57 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995090 | 1.00 | FKBP1A (0.57) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL8220787 | 0.89 | FKBP1A (0.54) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL8220783 | 0.89 | FKBP1A (0.54) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7984933 | 0.85 | MAPT (0.46) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL5847498 | 0.83 | FKBP1A (0.43) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7984949 | 0.79 | FKBP1A (0.61) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL5845846 | 0.76 | FKBP1A (0.46) | FKBP1A | |
| SCHEMBL30147174 | 0.74 | TSHR (0.49) | — | |
| SCHEMBL6100156 | 0.74 | FKBP1A (0.74) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL4679872 | 0.74 | FKBP1A (0.74) | FKBP1AMTORFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284779-B1 | NERVOUS SYSTEM DISORDERS | SCHERING AKTIIENGESELLSCHAFT (DE) | 2001-09-04 | — | — | US | claimed |
| US-6284779-B1 | NERVOUS SYSTEM DISORDERS | SCHERING AKTIIENGESELLSCHAFT (DE) | 2001-09-04 | — | — | US | disclosed |
| WO-2000046222-A1 | HETEROAROMATIC COMPOUNDS WITH NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-08-10 | — | — | WO | disclosed |