Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667159 | 0.89 | NCEH1 (0.56) | WDR5LDHANCEH1MEN1KMT2A | |
| SCHEMBL7988831 | 0.88 | MEN1 (0.48) | WDR5LDHANCEH1MEN1KMT2A | |
| SCHEMBL7982439 | 0.84 | WDR5 (0.61) | WDR5LDHAMEN1KMT2AKDM4E | |
| SCHEMBL13176746 | 0.81 | CA12 (0.55) | NCEH1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30512324 | 0.81 | MEN1 (0.51) | WDR5LDHANCEH1MEN1KMT2A | |
| SCHEMBL22650975 | 0.80 | MAPT (0.54) | WDR5LDHANCEH1MEN1KMT2A | |
| SCHEMBL6904390 | 0.80 | NCEH1 (0.52) | WDR5LDHANCEH1MEN1KMT2A | |
| SCHEMBL29404644 | 0.79 | NCEH1 (0.59) | WDR5NCEH1MEN1KMT2AKDM4E | |
| SCHEMBL71131 | 0.79 | NCEH1 (0.59) | WDR5NCEH1MEN1KMT2AKDM4E | |
| SCHEMBL27404692 | 0.79 | ALDH1A1 (0.47) | WDR5LDHANCEH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300340-B1 | USEFUL FOR THERAPY OF CANCER AND SOLID TUMORS | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| US-6162822-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 2000-12-19 | — | — | US | disclosed |
| US-5854273-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 1998-12-29 | — | — | US | disclosed |
| CN-1182086-A | New bisimide compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-05-20 | — | — | CN | disclosed |