Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984283 | 0.94 | CNOT7 (0.43) | KMT2AMEN1KDM4EP2RX7CNOT7 | |
| SCHEMBL7985065 | 0.90 | CNOT7 (0.40) | KMT2AMEN1CNOT7PARNMAPT | |
| SCHEMBL7974508 | 0.89 | CNOT7 (0.51) | KMT2AKDM4ECNOT7PARNALDH1A1 | |
| SCHEMBL7986522 | 0.89 | CNOT7 (0.48) | KMT2AMEN1KDM4EP2RX7CNOT7 | |
| SCHEMBL7984720 | 0.89 | CNOT7 (0.48) | CNOT7PARNALDH1A1ACP1TP53 | |
| SCHEMBL7987364 | 0.88 | TNKS (0.46) | KDM4ECNOT7PARNRIPK3ALDH1A1 | |
| SCHEMBL7985279 | 0.88 | CNOT7 (0.49) | KDM4ECNOT7PARNMAPK13GCGR | |
| SCHEMBL7985827 | 0.88 | CNOT7 (0.49) | KMT2AKDM4ECNOT7PARNMAPT | |
| SCHEMBL7988570 | 0.87 | HPGD (0.47) | KMT2AMEN1KDM4EP2RX7CNOT7 | |
| SCHEMBL7974471 | 0.87 | ACP1 (0.43) | KMT2AMEN1KDM4EP2RX7CNOT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |