Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988736 | 0.93 | ACP1 (0.45) | ACP1GRIN1GRIN2BPARNCNOT7 | |
| SCHEMBL7988962 | 0.91 | GRIN1 (0.44) | ACP1GRIN1GRIN2BMGAMGAA | |
| SCHEMBL7987255 | 0.91 | PARN (0.48) | ACP1GRIN1GRIN2BPARNCNOT7 | |
| SCHEMBL7991676 | 0.89 | ACP1 (0.43) | ACP1GRIN1GRIN2BPARNCNOT7 | |
| SCHEMBL7992270 | 0.89 | ABCC8 (0.43) | ACP1GRIN1GRIN2BPARNCNOT7 | |
| SCHEMBL7984427 | 0.89 | HPGD (0.44) | ACP1MEN1KMT2APARNCNOT7 | |
| SCHEMBL7991600 | 0.89 | ACP1 (0.42) | ACP1GRIN1GRIN2BMGAMGAA | |
| SCHEMBL7985568 | 0.88 | CNOT7 (0.41) | ACP1MGAMGAASIMGAM2 | |
| SCHEMBL7985168 | 0.87 | KMT2A (0.46) | ACP1MEN1KMT2APARNCNOT7 | |
| SCHEMBL7984720 | 0.87 | CNOT7 (0.48) | ACP1PARNCNOT7CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |