Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.43 |
| ▸ | PARN | O95453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985168 | 0.94 | KMT2A (0.46) | CNOT7PARNACP1KDM4EALDH1A1 | |
| SCHEMBL7974508 | 0.94 | CNOT7 (0.51) | CNOT7PARNSMN1; SMN2ACP1LMNA | |
| SCHEMBL7986522 | 0.94 | CNOT7 (0.48) | CNOT7PARNSMN1; SMN2HTTACP1 | |
| SCHEMBL7985279 | 0.93 | CNOT7 (0.49) | CNOT7PARNSMN1; SMN2HTTLMNA | |
| SCHEMBL7987364 | 0.91 | TNKS (0.46) | CNOT7PARNSMN1; SMN2HTTACP1 | |
| SCHEMBL7988644 | 0.89 | GRIN1 (0.42) | CNOT7PARNSMN1; SMN2ACP1ALDH1A1 | |
| SCHEMBL7988736 | 0.89 | ACP1 (0.45) | CNOT7PARNSMN1; SMN2HTTACP1 | |
| SCHEMBL7988820 | 0.88 | MAPK1 (0.48) | CNOT7PARNSMN1; SMN2HTTACP1 | |
| SCHEMBL7989422 | 0.87 | CNOT7 (0.47) | CNOT7PARNSMN1; SMN2HTTCYP11B2 | |
| SCHEMBL7974418 | 0.87 | CNOT7 (0.39) | CNOT7PARNSMN1; SMN2HTTACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |