Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.40 |
| ▸ | GCGR | P47871 | 3/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | FRK | P42685 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984283 | 0.93 | CNOT7 (0.43) | CNOT7KDM4EPARNHTTSMN1; SMN2 | |
| SCHEMBL7986522 | 0.90 | CNOT7 (0.48) | CNOT7KDM4EPARNHTTSMN1; SMN2 | |
| SCHEMBL7985827 | 0.89 | CNOT7 (0.49) | CNOT7KDM4EPARNMAPK14MAPK13 | |
| SCHEMBL7974444 | 0.88 | CNOT7 (0.52) | CNOT7KDM4EGSK3BPARNSMN1; SMN2 | |
| SCHEMBL7985168 | 0.88 | KMT2A (0.46) | CNOT7KDM4EPARNMAPK14MAPK13 | |
| SCHEMBL7974508 | 0.87 | CNOT7 (0.51) | CNOT7KDM4EPARNSMN1; SMN2LMNA | |
| SCHEMBL7985266 | 0.87 | CNOT7 (0.43) | CNOT7KDM4EPARNMAPK14MAPK13 | |
| SCHEMBL7989422 | 0.87 | CNOT7 (0.47) | CNOT7PARNDYRK1AHTTSMN1; SMN2 | |
| SCHEMBL7984934 | 0.86 | CNOT7 (0.47) | CNOT7KDM4EPARNGCGRLMNA | |
| SCHEMBL7987364 | 0.85 | TNKS (0.46) | CNOT7KDM4EPARNMAPK14HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |