Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 18/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12670878 | 0.85 | HSD11B1 (0.53) | HSD11B1 | |
| SCHEMBL7995131 | 0.81 | HSD11B1 (0.49) | HSD11B1 | |
| SCHEMBL12670877 | 0.81 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL7995217 | 0.81 | HSD11B1 (0.71) | HSD11B1 | |
| SCHEMBL7984098 | 0.79 | HSD11B1 (0.42) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL7988226 | 0.78 | GLA (0.47) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL7985222 | 0.78 | GLA (0.47) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL7991957 | 0.77 | HSD11B1 (0.43) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL7985356 | 0.76 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL7981860 | 0.75 | HSD11B1 (0.43) | GLAPOLBGAATSHRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |