Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991667 | 0.90 | ALDH1A1 (0.46) | GRIN1GRIN2BALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7989418 | 0.89 | SMN1; SMN2 (0.44) | GRIN1GRIN2BALDH1A1SMN1; SMN2CYP11B1 | |
| SCHEMBL7985261 | 0.89 | ALDH1A1 (0.44) | GRIN1GRIN2BALDH1A1SMN1; SMN2CYP11B1 | |
| SCHEMBL7985787 | 0.89 | SMN1; SMN2 (0.50) | GRIN1GRIN2BALDH1A1SMN1; SMN2CYP11B1 | |
| SCHEMBL7988656 | 0.88 | NPY5R (0.44) | GRIN1GRIN2BALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7988931 | 0.88 | GRIN1 (0.44) | GRIN1GRIN2BALDH1A1SMN1; SMN2CYP11B1 | |
| SCHEMBL7974283 | 0.88 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMT2ACNOT7PNP | |
| SCHEMBL7988635 | 0.87 | ALDH1A1 (0.45) | GRIN1GRIN2BALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7985297 | 0.86 | ALDH1A1 (0.43) | GRIN1GRIN2BALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7987428 | 0.86 | ROCK2 (0.57) | GAARXFP1KDM4CROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |