Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991608 | 0.95 | CNOT7 (0.47) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7985460 | 0.89 | CNOT7 (0.45) | CNOT7HTR2CSLC6A4GLSCACNA1G | |
| SCHEMBL7985320 | 0.86 | LMNA (0.47) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7974030 | 0.82 | CNOT7 (0.42) | CNOT7HTR2CSLC6A4GLSALDH1A1 | |
| SCHEMBL7988921 | 0.82 | CNOT7 (0.44) | CNOT7HTR2CSLC6A4ALDH1A1MCL1 | |
| SCHEMBL7975225 | 0.81 | CACNA1G (0.40) | LMNAPOLBHTR2CSLC6A4CACNA1G | |
| SCHEMBL7987945 | 0.81 | CACNA1G (0.39) | CNOT7LMNAHTR2CSLC6A4CACNA1G | |
| SCHEMBL7974180 | 0.81 | CNOT7 (0.44) | CNOT7HTR2CSLC6A4ALDH1A1MCL1 | |
| SCHEMBL7988124 | 0.81 | SMN1; SMN2 (0.41) | CNOT7MAPK1HTR2CSLC6A4CACNA1G | |
| SCHEMBL7991611 | 0.80 | HPGD (0.42) | CNOT7LMNAKDM4EPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |