Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.36 |
| ▸ | PARN | O95453 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992288 | 0.92 | ABCC8 (0.41) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7974301 | 0.92 | CACNA1G (0.40) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7985460 | 0.92 | CNOT7 (0.45) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7988124 | 0.87 | SMN1; SMN2 (0.41) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7987946 | 0.85 | HPGD (0.42) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7988929 | 0.84 | TP53 (0.43) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7975225 | 0.84 | CACNA1G (0.40) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7991608 | 0.83 | CNOT7 (0.47) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL7988921 | 0.83 | CNOT7 (0.44) | HTR2CSLC6A4CNOT7PARNP2RX7 | |
| SCHEMBL7974180 | 0.81 | CNOT7 (0.44) | HTR2CSLC6A4CNOT7PARNP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |