Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 7/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982563 | 0.94 | ALDH1A1 (0.51) | NPC1ALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL2094984 | 0.85 | NPSR1 (0.48) | NPC1ALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL2094982 | 0.84 | PTGIR (0.47) | NPC1ALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL7526392 | 0.83 | S100A4 (0.56) | NPC1ALDH1A1RAB9AHTTMEN1 | |
| SCHEMBL741752 | 0.82 | NPSR1 (0.64) | NPC1ALDH1A1RAB9AHTTMEN1 | |
| SCHEMBL1118819 | 0.82 | PTGIR (0.46) | NPC1ALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL2092944 | 0.81 | PTGIR (0.52) | KDM4EPTGIRPTGDRPTGER4PTGER3 | |
| Hydrochloric Acid SCHEMBL8550497 | 0.80 | NPSR1 (0.61) | NPC1ALDH1A1RAB9AHTTMEN1 | |
| SCHEMBL8044893 | 0.80 | NPSR1 (0.61) | NPC1ALDH1A1RAB9ALMNAHTT | |
| SCHEMBL27667245 | 0.80 | KMT2A (0.49) | NPC1ALDH1A1RAB9AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |