Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985347 | 0.94 | NPC1 (0.51) | ALDH1A1KDM4ENPC1LMNAPTBP1 | |
| SCHEMBL9687040 | 0.84 | CRHBP (0.56) | ALDH1A1KDM4ENPC1LMNAPTBP1 | |
| SCHEMBL27641818 | 0.84 | CES2 (0.45) | ALDH1A1KDM4ENPC1LMNAPTBP1 | |
| SCHEMBL17671204 | 0.82 | CES2 (0.44) | ALDH1A1KDM4ENPC1LMNAPTBP1 | |
| SCHEMBL7858429 | 0.82 | CES2 (0.44) | ALDH1A1KDM4ENPC1LMNAPTBP1 | |
| SCHEMBL7978952 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPC1LMNAPTBP1 | |
| SCHEMBL8640760 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPC1LMNAPTBP1 | |
| SCHEMBL2094984 | 0.78 | NPSR1 (0.48) | ALDH1A1KDM4ENPC1LMNAPTBP1 | |
| SCHEMBL8479231 | 0.78 | KEAP1 (0.42) | ALDH1A1KDM4ENPC1LMNAPTBP1 | |
| SCHEMBL30285727 | 0.78 | NPC1 (0.40) | ALDH1A1KDM4ENPC1LMNAPTBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1252068-A | 3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions containing the same | JAPAN TOBACCO INC (JP) | 2000-05-03 | — | — | CN | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |