Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974583 | 0.92 | GAA (0.59) | GAAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7985230 | 0.90 | ALDH1A1 (0.53) | GAAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7985702 | 0.88 | HPGD (0.50) | GAAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7974016 | 0.88 | GAA (0.56) | GAAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7985321 | 0.87 | SMN1; SMN2 (0.55) | GAAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7985844 | 0.86 | GAA (0.52) | GAAALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL7988610 | 0.85 | GUSB (0.54) | GAAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7975265 | 0.85 | SMN1; SMN2 (0.61) | GAAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7974404 | 0.85 | SMN1; SMN2 (0.49) | GAAALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7991871 | 0.84 | GAA (0.51) | GAAALDH1A1SMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |