Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985230 | 0.96 | ALDH1A1 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7975265 | 0.89 | SMN1; SMN2 (0.61) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7974016 | 0.89 | GAA (0.56) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7974583 | 0.89 | GAA (0.59) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7985355 | 0.88 | GAA (0.56) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7984716 | 0.88 | SMN1; SMN2 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2ATNKS | |
| SCHEMBL7991402 | 0.86 | SMN1; SMN2 (0.54) | HPGDALDH1A1SMN1; SMN2KMT2ATNKS | |
| SCHEMBL7974476 | 0.86 | GUSB (0.56) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7986518 | 0.85 | SMN1; SMN2 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2ATNKS | |
| SCHEMBL7974486 | 0.85 | SMN1; SMN2 (0.50) | HPGDALDH1A1SMN1; SMN2KMT2ATNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |