Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987312 | 0.96 | GRIN1 (0.48) | GRIN1GRIN2BPOLBTHRBYTHDC1 | |
| SCHEMBL7991676 | 0.93 | ACP1 (0.43) | GRIN1GRIN2BACP1PARNCNOT7 | |
| SCHEMBL7973628 | 0.93 | SMN1; SMN2 (0.48) | YTHDC1GLAHTTUBE2NSMN1; SMN2 | |
| SCHEMBL7988784 | 0.92 | MAPK1 (0.43) | GRIN1GRIN2BYTHDC1GLAHTT | |
| SCHEMBL7974015 | 0.91 | PARN (0.49) | GLAHTTUBE2NSMN1; SMN2L3MBTL1 | |
| SCHEMBL7985794 | 0.90 | PARN (0.46) | GRIN1GRIN2BSMN1; SMN2PARNCNOT7 | |
| SCHEMBL7987255 | 0.90 | PARN (0.48) | GRIN1GRIN2BSMN1; SMN2ACP1MAPK1 | |
| SCHEMBL7985302 | 0.89 | ROCK2 (0.41) | GRIN1GRIN2BACP1PARNCNOT7 | |
| SCHEMBL7988820 | 0.89 | MAPK1 (0.48) | GRIN1GRIN2BYTHDC1GLAHTT | |
| SCHEMBL7991638 | 0.88 | GRIN1 (0.42) | GRIN1GRIN2BACP1PARNCNOT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |