Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985362 | 0.92 | GRIN1 (0.45) | MAPK1ACP1GRIN1GRIN2BYTHDC1 | |
| SCHEMBL7988736 | 0.92 | ACP1 (0.45) | MAPK1USP2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7988820 | 0.91 | MAPK1 (0.48) | MAPK1ACP1GRIN1GRIN2BYTHDC1 | |
| SCHEMBL7973628 | 0.90 | SMN1; SMN2 (0.48) | MAPK1ACP1YTHDC1PARNCNOT7 | |
| SCHEMBL7974015 | 0.90 | PARN (0.49) | MAPK1USP2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7987312 | 0.90 | GRIN1 (0.48) | MAPK1ACP1GRIN1GRIN2BYTHDC1 | |
| SCHEMBL7974418 | 0.90 | CNOT7 (0.39) | USP2ACP1PARNCNOT7SMN1; SMN2 | |
| SCHEMBL7991600 | 0.90 | ACP1 (0.42) | ACP1GRIN1GRIN2BYTHDC1PARN | |
| SCHEMBL7985619 | 0.89 | CNOT7 (0.41) | ACP1PARNCNOT7LMNAIDO1 | |
| SCHEMBL7986522 | 0.88 | CNOT7 (0.48) | MAPK1USP2CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |