Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7980310 | 0.82 | DRD2 (0.44) | DRD2SLC6A4CCR5ACVR1HRH3 | |
| Hydrochloric Acid SCHEMBL7968861 | 0.81 | DRD2 (0.40) | DRD2SLC6A4CCR5OPRM1ACVR1 | |
| Hydrochloric Acid SCHEMBL7982395 | 0.81 | DRD2 (0.42) | DRD2SLC6A4CCR5OPRM1ACVR1 | |
| SCHEMBL27538654 | 0.78 | CCR5 (0.41) | DRD2SLC6A4CCR5ACVR1HRH3 | |
| SCHEMBL7982321 | 0.76 | DRD2 (0.43) | DRD2SLC6A4CCR5OPRM1ACVR1 | |
| Hydrochloric Acid SCHEMBL7978864 | 0.76 | CCR5 (0.47) | DRD2SLC6A4CCR5ACVR1HRH3 | |
| SCHEMBL11562263 | 0.72 | ACHE (0.54) | DRD2SLC6A4CCR5ACVR1ACHE | |
| Hydrochloric Acid SCHEMBL7982489 | 0.71 | DRD2 (0.46) | DRD2SLC6A4CCR5ACVR1HRH3 | |
| Hydrochloric Acid SCHEMBL7982454 | 0.71 | CCR5 (0.49) | DRD2SLC6A4CCR5ACVR1HRH3 | |
| SCHEMBL11567913 | 0.71 | ACHE (0.57) | DRD2SLC6A4CCR5ACHEHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |