Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 16/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137546 | 0.88 | SLC9A1 (0.53) | SLC9A1CYP3A4CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL27488942 | 0.86 | SLC9A1 (0.52) | SLC9A1CYP3A4CYP2C19CYP2C9NPY2R | |
| SCHEMBL6137374 | 0.85 | SLC9A1 (0.73) | SLC9A1CYP3A4CYP2C19CYP2C9NPY2R | |
| SCHEMBL7988906 | 0.84 | SLC9A1 (0.51) | SLC9A1CYP3A4CYP2C19 | |
| SCHEMBL27488943 | 0.79 | SLC9A1 (0.45) | SLC9A1CYP3A4CYP2C19NPY2R | |
| SCHEMBL6137505 | 0.78 | SLC9A1 (0.42) | SLC9A1CYP3A4CYP2C19NPY2R | |
| SCHEMBL7982517 | 0.77 | RBP4 (0.54) | SLC9A1CYP3A4CYP2C19NPY2R | |
| SCHEMBL7985442 | 0.74 | SLC9A1 (0.53) | SLC9A1CYP3A4CYP2C19CYP2C9NPY2R | |
| Sabiporide SCHEMBL27472449 | 0.73 | SLC9A1 (0.89) | SLC9A1CYP3A4CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL5950962 | 0.71 | SLC9A1 (0.73) | SLC9A1CYP3A4CYP2C19CYP2C9NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323207-B1 | TREATMENT OR REDUCTION OF TISSUE DAMAGE DUE TO ISCHAEMIA WHICH COMPRISES ADMINISTERING TO A HOST SUFFERING FROM ISCHAEMIA | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-27 | — | — | US | disclosed |