Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137546 | 0.86 | SLC9A1 (0.53) | SLC9A1CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL6137374 | 0.85 | SLC9A1 (0.73) | SLC9A1CYP3A4CYP2C19CA12CA1 | |
| SCHEMBL7985443 | 0.84 | SLC9A1 (0.51) | SLC9A1CYP3A4CYP2C19 | |
| SCHEMBL27522789 | 0.78 | ALDH1A1 (0.51) | SLC9A1CYP3A4CYP2C19ALDH1A1MAPT | |
| SCHEMBL6137327 | 0.78 | ALDH1A1 (0.47) | SLC9A1CYP3A4CYP2C19ALDH1A1MAPT | |
| SCHEMBL7612077 | 0.77 | MAPT (0.52) | SLC9A1CYP3A4CYP2C19ALDH1A1MAPT | |
| SCHEMBL7971257 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL2683734 | 0.73 | SLC9A1 (0.66) | SLC9A1CYP3A4CYP2C19ALDH1A1MAPT | |
| Sabiporide SCHEMBL27472449 | 0.71 | SLC9A1 (0.89) | SLC9A1CYP3A4CYP2C19 | |
| SCHEMBL7985442 | 0.71 | SLC9A1 (0.53) | SLC9A1CYP3A4CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323207-B1 | TREATMENT OR REDUCTION OF TISSUE DAMAGE DUE TO ISCHAEMIA WHICH COMPRISES ADMINISTERING TO A HOST SUFFERING FROM ISCHAEMIA | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-27 | — | — | US | disclosed |