Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988917 | 0.91 | HTR2C (0.40) | HTR2CSLC6A4MCL1HPGDSMN1; SMN2 | |
| SCHEMBL7987944 | 0.91 | HTR2C (0.38) | HTR2CSLC6A4MCL1HPGDSMN1; SMN2 | |
| SCHEMBL7988121 | 0.91 | SMN1; SMN2 (0.41) | HTR2CSLC6A4MCL1SMN1; SMN2GAA | |
| SCHEMBL7991605 | 0.90 | HTR2C (0.41) | HTR2CSLC6A4MCL1ALDH1A1GLS | |
| SCHEMBL7974300 | 0.90 | HTR2C (0.37) | HTR2CSLC6A4MCL1HPGDALDH1A1 | |
| SCHEMBL7992285 | 0.90 | ABCC8 (0.41) | HTR2CSLC6A4MCL1HPGDKMT2A | |
| SCHEMBL7974025 | 0.90 | HTR2C (0.39) | HTR2CSLC6A4MCL1HPGDSMN1; SMN2 | |
| SCHEMBL7974177 | 0.89 | MCL1 (0.41) | HTR2CSLC6A4MCL1HPGDSMN1; SMN2 | |
| SCHEMBL7975222 | 0.89 | MCL1 (0.39) | HTR2CSLC6A4MCL1ALDH1A1 | |
| SCHEMBL7985311 | 0.89 | HTR2C (0.40) | HTR2CSLC6A4MCL1ALDH1A1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |