Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992285 | 0.91 | ABCC8 (0.41) | HTR2CSLC6A4MCL1LMNAHPGD | |
| SCHEMBL7974300 | 0.91 | HTR2C (0.37) | HTR2CSLC6A4MCL1CYP11B1CYP11B2 | |
| SCHEMBL7985457 | 0.91 | HTR2C (0.46) | HTR2CSLC6A4MCL1SMN1; SMN2HPGD | |
| SCHEMBL7988121 | 0.86 | SMN1; SMN2 (0.41) | HTR2CSLC6A4MCL1HTTSMN1; SMN2 | |
| SCHEMBL7975222 | 0.84 | MCL1 (0.39) | HTR2CSLC6A4MCL1LMNATP53 | |
| SCHEMBL7988928 | 0.83 | GAA (0.44) | HTR2CSLC6A4MCL1HPGDTP53 | |
| SCHEMBL7988917 | 0.83 | HTR2C (0.40) | HTR2CSLC6A4MCL1SMN1; SMN2HPGD | |
| SCHEMBL7987946 | 0.82 | HPGD (0.42) | HTR2CSLC6A4MCL1LMNACYP11B1 | |
| SCHEMBL7991605 | 0.82 | HTR2C (0.41) | HTR2CSLC6A4MCL1 | |
| SCHEMBL7974025 | 0.81 | HTR2C (0.39) | HTR2CSLC6A4MCL1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |