Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7988733 | 0.99 | CNOT7 (0.40) | CNOT7PARNKDM4EALDH1A1CYP11B2 | |
| SCHEMBL7988039 | 0.89 | CNOT7 (0.41) | CNOT7PARNKDM4EALDH1A1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7988145 | 0.88 | CNOT7 (0.40) | CNOT7PARNKDM4EALDH1A1CYP11B2 | |
| SCHEMBL7984366 | 0.88 | CNOT7 (0.53) | CNOT7PARNALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL7984530 | 0.88 | HPGD (0.46) | CNOT7PARNKDM4EALDH1A1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7992068 | 0.87 | CNOT7 (0.52) | CNOT7PARNALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL7989504 | 0.87 | GRIN1 (0.41) | CNOT7PARNKDM4EALDH1A1P2RX7 | |
| SCHEMBL7991686 | 0.86 | ABCC8 (0.48) | CNOT7PARNCYP11B2SMN1; SMN2RXFP1 | |
| SCHEMBL7988961 | 0.86 | KDM4E (0.42) | CNOT7PARNKDM4EALDH1A1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7985467 | 0.85 | ABCC8 (0.47) | CNOT7PARNCYP11B2SMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |