Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978954 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL7985661 | 0.84 | TSHR (0.43) | ALDH1A1TSHRKMT2AMEN1GAA | |
| SCHEMBL7985664 | 0.83 | HDAC6 (0.44) | ALDH1A1TSHRKMT2AGAAHDAC6 | |
| SCHEMBL7978926 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL7978886 | 0.80 | KMT2A (0.48) | ALDH1A1TSHRKMT2AMEN1GAA | |
| SCHEMBL8691853 | 0.79 | KMT2A (0.41) | ALDH1A1TSHRKMT2AMEN1GAA | |
| SCHEMBL7978951 | 0.79 | POLQ (0.42) | ALDH1A1TSHRKMT2AMEN1GAA | |
| Hydrochloric Acid SCHEMBL7846316 | 0.78 | GAA (0.39) | ALDH1A1TSHRKMT2AMEN1GAA | |
| SCHEMBL7982076 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2AMEN1GAA | |
| SCHEMBL15206612 | 0.78 | TDP1 (0.51) | ALDH1A1TSHRKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1252068-A | 3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions containing the same | JAPAN TOBACCO INC (JP) | 2000-05-03 | — | — | CN | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |