Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985647 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1TSHRLMNAL3MBTL1 | |
| SCHEMBL15206612 | 0.80 | TDP1 (0.51) | KMT2AMEN1TSHRLMNAL3MBTL1 | |
| SCHEMBL7978926 | 0.79 | ALDH1A1 (0.43) | KMT2AMEN1TSHRLMNATRPM8 | |
| SCHEMBL7978954 | 0.79 | ALDH1A1 (0.43) | KMT2AMEN1TSHRLMNAL3MBTL1 | |
| SCHEMBL31393778 | 0.76 | PAX8 (0.56) | KMT2AMEN1TSHRTRPM8ALDH1A1 | |
| SCHEMBL7978951 | 0.75 | POLQ (0.42) | KMT2AMEN1TSHRALDH1A1NPC1 | |
| SCHEMBL8691853 | 0.75 | KMT2A (0.41) | KMT2AMEN1TSHRALDH1A1NPC1 | |
| SCHEMBL7968895 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL11617034 | 0.72 | ADORA2A (0.49) | TSHRLMNAL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7968912 | 0.72 | ALDH1A1 (0.42) | KMT2AMEN1TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |