Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 2/20 | 0.42 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985861 | 0.84 | CNOT7 (0.44) | DHPSCNOT7POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7974286 | 0.81 | DHPS (0.49) | DHPSCNOT7POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7985471 | 0.81 | HPGD (0.43) | CNOT7POLBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7975252 | 0.80 | HPGD (0.45) | CNOT7POLBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7988099 | 0.80 | SMN1; SMN2 (0.45) | CNOT7SMN1; SMN2ALDH1A1HPGDCYP11B1 | |
| SCHEMBL7984365 | 0.80 | HPGD (0.45) | CNOT7SMN1; SMN2ALDH1A1HPGDCYP11B1 | |
| SCHEMBL7974515 | 0.80 | GAA (0.48) | SMN1; SMN2ALDH1A1HPGDCYP11B1CYP11B2 | |
| SCHEMBL7989407 | 0.79 | HPGD (0.44) | CNOT7POLBSMN1; SMN2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7987467 | 0.79 | SMN1; SMN2 (0.44) | CNOT7SMN1; SMN2ALDH1A1HPGDCYP11B1 | |
| Hydrochloric Acid SCHEMBL7992066 | 0.79 | HPGD (0.44) | CNOT7SMN1; SMN2ALDH1A1HPGDCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |