Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985225 | 0.83 | GAA (0.48) | GAAHPGDCYP11B1CYP11B2CYP1A2 | |
| SCHEMBL7985705 | 0.83 | CYP11B1 (0.49) | GAAHPGDCYP11B1CYP11B2CYP1A2 | |
| SCHEMBL7985343 | 0.82 | GAA (0.44) | GAAHPGDCYP11B1CYP11B2RXFP1 | |
| SCHEMBL7987782 | 0.81 | NPC1 (0.44) | GAAHPGDCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL7975252 | 0.81 | HPGD (0.45) | GAAHPGDCYP11B1CYP11B2RXFP1 | |
| SCHEMBL7984365 | 0.80 | HPGD (0.45) | GAAHPGDCYP11B1CYP11B2CTSL | |
| SCHEMBL7989407 | 0.80 | HPGD (0.44) | GAAHPGDCYP11B1CYP11B2RXFP1 | |
| SCHEMBL7985684 | 0.80 | DHPS (0.42) | HPGDCYP11B1CYP11B2CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL7992066 | 0.79 | HPGD (0.44) | GAAHPGDCYP11B1CYP11B2CTSL | |
| SCHEMBL7985471 | 0.79 | HPGD (0.43) | GAAHPGDCYP11B1CYP11B2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |