Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984440 | 0.86 | PDE4A (0.40) | TP53ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7974271 | 0.85 | TNF (0.46) | SMN1; SMN2TP53TSHRALDH1A1LMNA | |
| SCHEMBL7975252 | 0.83 | HPGD (0.45) | CYP11B1CYP11B2SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7984788 | 0.81 | CYP11B1 (0.45) | CYP11B1CYP11B2SMN1; SMN2TP53TSHR | |
| SCHEMBL7987434 | 0.80 | CYP11B1 (0.42) | CYP11B1CYP11B2SMN1; SMN2TP53TSHR | |
| SCHEMBL7973934 | 0.79 | CYP11B1 (0.45) | CYP11B1CYP11B2SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7987960 | 0.79 | CYP11B1 (0.32) | CYP11B1CYP11B2LMNA | |
| SCHEMBL7985554 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53TSHRALDH1A1KMT2A | |
| SCHEMBL7974260 | 0.78 | CYP11B1 (0.47) | CYP11B1CYP11B2SMN1; SMN2TP53TSHR | |
| SCHEMBL7985651 | 0.78 | CYP1A2 (0.41) | SMN1; SMN2ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |