Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975252 | 0.86 | HPGD (0.45) | GAAALDH1A1SMN1; SMN2KMT2APKM | |
| SCHEMBL7973934 | 0.84 | CYP11B1 (0.45) | PDE10ATRPA1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7988129 | 0.84 | MET (0.44) | CYP1A2GAAALDH1A1SMN1; SMN2MET | |
| SCHEMBL7974260 | 0.83 | CYP11B1 (0.47) | CYP1A2ADORA2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7984512 | 0.83 | GAA (0.50) | ADORA2AGAAKMT2A | |
| SCHEMBL7987434 | 0.83 | CYP11B1 (0.42) | CYP1A2CYP19A1TRPA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7984208 | 0.82 | MAPT (0.39) | CYP1A2GAAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL7984754 | 0.82 | SMN1; SMN2 (0.47) | ADORA2AGAASMN1; SMN2 | |
| SCHEMBL7987782 | 0.82 | NPC1 (0.44) | CYP1A2PTGDR2GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7984526 | 0.81 | MET (0.46) | ALDH1A1SMN1; SMN2METKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |