Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1288390 | 1.00 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19PSEN1PSEN2 | |
| SCHEMBL416422 | 0.89 | OPRM1 (0.50) | CYP3A4CYP2C9CYP2C19PSEN1PSEN2 | |
| Ethylene SCHEMBL7936439 | 0.86 | OPRM1 (0.48) | CYP3A4CYP2C9CYP2C19PSEN1PSEN2 | |
| SCHEMBL425330 | 0.85 | CTSL (0.50) | CYP3A4CYP2C9CYP2C19PSEN1PSEN2 | |
| SCHEMBL420469 | 0.83 | PSEN1 (0.50) | CYP3A4CYP2C9CYP2C19PSEN1PSEN2 | |
| SCHEMBL418931 | 0.83 | SIGMAR1 (0.41) | CYP3A4CYP2C9CYP2C19PSEN1PSEN2 | |
| SCHEMBL7753890 | 0.81 | ESR2 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL23258242 | 0.79 | CARM1 (0.46) | CYP2C19PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21004783 | 0.79 | SIGMAR1 (0.43) | CYP3A4CYP2C19PSEN1PSEN2APH1B | |
| SCHEMBL29207685 | 0.79 | CTSL (0.41) | CYP2C19PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6287829-B1 | USING CHIRAL ANCHOR-PROTECTIVE GROUPS | DSM FINE CHEMICAL AUSTRIA NFG GMBH & CO KG (AT) | 2001-09-11 | — | — | US | disclosed |
| EP-0970235-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROXYLATION OF ALDEHYDES AND KETONES | DSM Fine Chemicals Austria GmbH (AT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998041647-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROXYLATION OF ALDEHYDES AND KETONES | DSM CHEMIE LINZ GMBH (AT) | 1998-09-24 | — | — | WO | disclosed |